
DLCO variability in the real world: quality, interpretation, and evidence-linked cutoffs
DLCO is one of the most useful numbers in lung testing — but it’s also one of the most misunderstood. Many patients and even clinicians notice DLCO values “bounce” between tests. Is that real change or just measurement noise?. Recent evidence shows that inter-session differences can exceed traditional thresholds for a meaningful change. Absolute shifts beyond 3.5 mL/min/mm Hg, 15









